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Recent Insights from Molecular Dynamics Simulations for G Protein-Coupled Receptor Drug Discovery
G protein-coupled receptors (GPCRs) are critical drug targets. GPCRs convey signals from the extracellular to the intracellular environment through G proteins. Some ligands that bind to GPCRs activate different downstream signaling pathways. G protein activation, or β-arrestin biased signaling, invo...
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| 出版年: | Int J Mol Sci |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6747122/ https://ncbi.nlm.nih.gov/pubmed/31470676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20174237 |
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