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An increased cell cycle gene network determines MEK and Akt inhibitor double resistance in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with poor clinical prognosis and limited targeted treatment strategies. Kinase inhibitor screening of a panel of 20 TNBC cell lines uncovered three critical TNBC subgroups: 1) sensitive to only MEK inhibitors; 2) sensitiv...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6746778/ https://ncbi.nlm.nih.gov/pubmed/31527768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49809-3 |
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