Loading...
Retinal guanylyl cyclase activation by calcium sensor proteins mediates photoreceptor degeneration in an rd3 mouse model of congenital human blindness
Deficiency of RD3 (retinal degeneration 3) protein causes recessive blindness and photoreceptor degeneration in humans and in the rd3 mouse strain, but the disease mechanism is unclear. Here, we present evidence that RD3 protects photoreceptors from degeneration by competing with guanylyl cyclase-ac...
Saved in:
| Published in: | J Biol Chem |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2019
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6746453/ https://ncbi.nlm.nih.gov/pubmed/31346032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009948 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|