Enantioselective Synthesis of Homoisoflavanones by Asymmetric Transfer Hydrogenation and Their Biological Evaluation for Antiangiogenic Activity

Neovascular eye diseases are a major cause of blindness. Excessive angiogenesis is a feature of several conditions, including wet age-related macular degeneration, proliferative diabetic retinopathy, and retinopathy of prematurity. Development of novel anti-angiogenic small molecules for the treatme...

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Publicado en:J Org Chem
Autores principales: Heo, Myunghoe, Lee, Bit, Sishtla, Kamakshi, Fei, Xiang, Lee, Sanha, Park, Soojun, Yuan, Yue, Lee, Seul, Kwon, Sang-Il, Lee, Jungeun, Kim, Sanghee, Corson, Timothy W., Seo, Seung-Yong
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746246/
https://ncbi.nlm.nih.gov/pubmed/31381339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b01134
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