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First Synthesis of the Antiangiogenic Homoisoflavanone, Cremastranone

An antiangiogenic homoisoflavanone, cremastranone, was synthesized for the first time. This scalable synthesis, which includes selective demethylation, could be used to develop lead molecules to treat angiogenesis-induced eye diseases. Synthetic cremastranone inhibited the proliferation, migration a...

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Detalhes bibliográficos
Main Authors: Lee, Bit, Basavarajappa, Halesha D., Sulaiman, Rania S., Fei, Xiang, Seo, Seung-Yong, Corson, Timothy W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167916/
https://ncbi.nlm.nih.gov/pubmed/25167470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob01604a
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