Immunophenotype of a Rat Model of Duchenne's Disease and Demonstration of Improved Muscle Strength After Anti-CD45RC Antibody Treatment

Corticosteroids (CS) are standard therapy for the treatment of Duchenne's muscular dystrophy (DMD). Even though they decrease inflammation, they have limited efficacy and are associated with significant side effects. There is therefore the need for new protolerogenic treatments to replace CS. D...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Ouisse, Laure-Hélène, Remy, Séverine, Lafoux, Aude, Larcher, Thibaut, Tesson, Laurent, Chenouard, Vanessa, Guillonneau, Carole, Brusselle, Lucas, Vimond, Nadège, Rouger, Karl, Péréon, Yann, Chenouard, Alexis, Gras-Le Guen, Christèle, Braudeau, Cécile, Josien, Régis, Huchet, Corinne, Anegon, Ignacio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746111/
https://ncbi.nlm.nih.gov/pubmed/31552055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02131
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