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LSD1 Inhibition Prolongs Survival in Mouse Models of MPN by Selectively Targeting the Disease Clone

Despite recent advances, the myeloproliferative neoplasms (MPNs) are attended by considerable morbidity and mortality. Janus kinase (Jak) inhibitors such as ruxolitinib manage symptoms but do not substantially change the natural history of the disease. In this report, we show the effects of IMG-7289...

詳細記述

保存先:
書誌詳細
出版年:Hemasphere
主要な著者: Jutzi, Jonas S., Kleppe, Maria, Dias, Jennifer, Staehle, Hans Felix, Shank, Kaitlyn, Teruya-Feldstein, Julie, Gambheer, Sudheer Madan Mohan, Dierks, Christine, Rienhoff, Hugh Y., Levine, Ross L., Pahl, Heike L.
フォーマット: Artigo
言語:Inglês
出版事項: Wolters Kluwer Health 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745991/
https://ncbi.nlm.nih.gov/pubmed/31723778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HS9.0000000000000054
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