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CAR T Cells: A Snapshot on the Growing Options to Design a CAR

Adoptive cell therapy of malignant diseases with chimeric antigen receptor (CAR) modified T cells rapidly advanced from pre-clinical models to commercial approvals within 2 decades. CARs redirect patient's T cells towards cancer cells and activate the engineered cells for a cytolytic attack res...

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Detalhes bibliográficos
Publicado no:Hemasphere
Main Authors: Holzinger, Astrid, Abken, Hinrich
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745938/
https://ncbi.nlm.nih.gov/pubmed/31723811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HS9.0000000000000172
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