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In Vitro and in Vivo antitumor activity and the mechanism of siphonodictyal B in human colon cancer cells
Liphagal, isolated from the marine sponge Aka coralliphaga, exhibits phosphatidylinositol 3‐kinase alpha (PI3Kα) inhibitory activity and cytotoxic effects in human cancer cells. Siphonodictyal B, the biogenetic precursor of liphagal, also has PI3K inhibitory activity. However, its cytotoxic or antit...
Gespeichert in:
| Veröffentlicht in: | Cancer Med |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6745845/ https://ncbi.nlm.nih.gov/pubmed/31364822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2409 |
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