Recombinant Slit2 attenuates neuronal apoptosis via the Robo1-srGAP1 pathway in a rat model of neonatal HIE

Apoptosis following hypoxic-ischemic injury to the brain plays a major role in neuronal cell death. The neonatal brain is more susceptible to injury as the cortical neurons are immature and there are lower levels of antioxidants. Slit2, an extracellular matrix protein, has been shown to be neuroprot...

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Vydáno v:Neuropharmacology
Hlavní autoři: Kaur, Harpreet, Xu, Ningbo, Doycheva, Desislava Met, Malaguit, Jay, Tang, Jiping, Zhang, John H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745244/
https://ncbi.nlm.nih.gov/pubmed/31356825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2019.107727
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