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Mind the (sr)GAP – roles of Slit–Robo GAPs in neurons, brains and beyond

The Slit–Robo GTPase-activating proteins (srGAPs) were first identified as potential Slit–Robo effectors that influence growth cone guidance. Given their N-terminal F-BAR, central GAP and C-terminal SH3 domains, srGAPs have the potential to affect membrane dynamics, Rho family GTPase activity and ot...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Lucas, Bethany, Hardin, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769592/
https://ncbi.nlm.nih.gov/pubmed/29097383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.207456
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