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Simultaneous molecular docking of different ligands to His(6)-tagged organophosphorus hydrolase as an effective tool for assessing their effect on the enzyme

BACKGROUND: Enzymatic hydrolysis of N-acyl homoserine lactones (AHLs), which are signaling molecules responsible for the development of antibiotic resistance in gram-negative bacteria, is a potential solution to overcoming antibiotic resistance problem. It has been established that hexahistidine-tag...

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Publicat a:PeerJ
Autors principals: Aslanli, Aysel, Efremenko, Elena
Format: Artigo
Idioma:Inglês
Publicat: PeerJ Inc. 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745196/
https://ncbi.nlm.nih.gov/pubmed/31565584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.7684
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