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Simultaneous molecular docking of different ligands to His(6)-tagged organophosphorus hydrolase as an effective tool for assessing their effect on the enzyme

BACKGROUND: Enzymatic hydrolysis of N-acyl homoserine lactones (AHLs), which are signaling molecules responsible for the development of antibiotic resistance in gram-negative bacteria, is a potential solution to overcoming antibiotic resistance problem. It has been established that hexahistidine-tag...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Aslanli, Aysel, Efremenko, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745196/
https://ncbi.nlm.nih.gov/pubmed/31565584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.7684
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