Endo-lysosomal proteins and ubiquitin CSF concentrations in Alzheimer’s and Parkinson’s disease

BACKGROUND: Increasing evidence implicates dysfunctional proteostasis and the involvement of the autophagic and endo-lysosomal system and the ubiquitin-proteasome system in neurodegenerative diseases. In Alzheimer’s disease (AD), there is an accumulation of autophagic vacuoles within the neurons. In...

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Publicado en:Alzheimers Res Ther
Autores principales: Sjödin, Simon, Brinkmalm, Gunnar, Öhrfelt, Annika, Parnetti, Lucilla, Paciotti, Silvia, Hansson, Oskar, Hardy, John, Blennow, Kaj, Zetterberg, Henrik, Brinkmalm, Ann
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745076/
https://ncbi.nlm.nih.gov/pubmed/31521194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0533-9
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