CSF evidence of pericyte damage in Alzheimer’s disease is associated with markers of blood-brain barrier dysfunction and disease pathology

BACKGROUND: We aimed to assess the relationship between levels of a cerebrospinal fluid (CSF) marker of pericyte damage, soluble platelet-derived growth factor receptor β (sPDGFRβ) and CSF markers of blood-brain barrier (BBB) integrity (CSF albumin and CSF/serum albumin ratio) and disease pathology...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Miners, J. S., Kehoe, P. G., Love, S., Zetterberg, H., Blennow, K.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745071/
https://ncbi.nlm.nih.gov/pubmed/31521199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0534-8
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