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Differing associations between Aβ accumulation, hypoperfusion, blood–brain barrier dysfunction and loss of PDGFRB pericyte marker in the precuneus and parietal white matter in Alzheimer's disease

Recent studies implicate loss of pericytes in hypoperfusion and blood–brain barrier (BBB) leakage in Alzheimer's disease (AD). In this study, we have measured levels of the pericyte marker, platelet-derived growth factor receptor-β (PDGFRB), and fibrinogen (to assess blood–brain barrier leakage...

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Detalles Bibliográficos
Publicado en:J Cereb Blood Flow Metab
Main Authors: Miners, J Scott, Schulz, Isabel, Love, Seth
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757436/
https://ncbi.nlm.nih.gov/pubmed/28151041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17690761
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