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Differing associations between Aβ accumulation, hypoperfusion, blood–brain barrier dysfunction and loss of PDGFRB pericyte marker in the precuneus and parietal white matter in Alzheimer's disease
Recent studies implicate loss of pericytes in hypoperfusion and blood–brain barrier (BBB) leakage in Alzheimer's disease (AD). In this study, we have measured levels of the pericyte marker, platelet-derived growth factor receptor-β (PDGFRB), and fibrinogen (to assess blood–brain barrier leakage...
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Publicado en: | J Cereb Blood Flow Metab |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
SAGE Publications
2017
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5757436/ https://ncbi.nlm.nih.gov/pubmed/28151041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17690761 |
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