Survival after bilateral risk-reducing mastectomy in healthy BRCA1 and BRCA2 mutation carriers

BACKGROUND: In healthy BRCA1/2 mutation carriers, bilateral risk-reducing mastectomy (BRRM) strongly reduces the risk of developing breast cancer (BC); however, no clear survival benefit of BRRM over BC surveillance has been reported yet. METHODS: In this Dutch multicenter cohort study, we used mult...

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Dettagli Bibliografici
Pubblicato in:Breast Cancer Res Treat
Autori principali: Heemskerk-Gerritsen, Bernadette A. M., Jager, Agnes, Koppert, Linetta B., Obdeijn, A. Inge-Marie, Collée, Margriet, Meijers-Heijboer, Hanne E. J., Jenner, Denise J., Oldenburg, Hester S. A., van Engelen, Klaartje, de Vries, Jakob, van Asperen, Christi J., Devilee, Peter, Blok, Marinus J., Kets, C. Marleen, Ausems, Margreet G. E. M., Seynaeve, Caroline, Rookus, Matti A., Hooning, Maartje J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2019
Soggetti:
Epidemiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745043/
https://ncbi.nlm.nih.gov/pubmed/31302855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-019-05345-2
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