Survival after bilateral risk-reducing mastectomy in healthy BRCA1 and BRCA2 mutation carriers

BACKGROUND: In healthy BRCA1/2 mutation carriers, bilateral risk-reducing mastectomy (BRRM) strongly reduces the risk of developing breast cancer (BC); however, no clear survival benefit of BRRM over BC surveillance has been reported yet. METHODS: In this Dutch multicenter cohort study, we used mult...

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Udgivet i:Breast Cancer Res Treat
Main Authors: Heemskerk-Gerritsen, Bernadette A. M., Jager, Agnes, Koppert, Linetta B., Obdeijn, A. Inge-Marie, Collée, Margriet, Meijers-Heijboer, Hanne E. J., Jenner, Denise J., Oldenburg, Hester S. A., van Engelen, Klaartje, de Vries, Jakob, van Asperen, Christi J., Devilee, Peter, Blok, Marinus J., Kets, C. Marleen, Ausems, Margreet G. E. M., Seynaeve, Caroline, Rookus, Matti A., Hooning, Maartje J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2019
Fag:
Epidemiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745043/
https://ncbi.nlm.nih.gov/pubmed/31302855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-019-05345-2
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