Lower mitotic activity in BRCA1/2-associated primary breast cancers occurring after risk-reducing salpingo-oophorectomy

Risk-reducing salpingo-oophorectomy (RRSO) is associated with 50% reduction of BRCA1/2-associated breast cancer (BC) risk, possibly through decreased growth activity. In this pilot study, tumor characteristics and growth rates of BRCA1/2-associated primary BCs (PBCs) detected after RRSO were compare...

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Dades bibliogràfiques
Autors principals: van Verschuer, Victorien MT, Heemskerk-Gerritsen, Bernadette AM, van Deurzen, Carolien HM, Obdeijn, Inge-Marie, Tilanus-Linthorst, Madeleine MA, Verhoef, Cornelis, Schmidt, Marjanka K, Koppert, Linetta B, Hooning, Maartje J, Seynaeve, Caroline
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2014
Matèries:
Clinical Study
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979814/
https://ncbi.nlm.nih.gov/pubmed/24423863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.27628
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