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Toxicity of (neo)adjuvant chemotherapy for BRCA1- and BRCA2-associated breast cancer
Treatment with (neo)adjuvant chemotherapy for breast cancer, as currently given, causes cell damage by induction of double-strand DNA breaks. Because BRCA1 and BRCA2 proteins play a role in the repair of DNA damage, the efficacy of (neo)adjuvant chemotherapy may be increased in BRCA1/2-associated br...
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| 發表在: | Breast Cancer Res Treat |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Springer US
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4837227/ https://ncbi.nlm.nih.gov/pubmed/27060914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-016-3777-0 |
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