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Integrative molecular characterization of resistance to neoadjuvant chemoradiation in rectal cancer

PURPOSE: Molecular properties associated with complete response or acquired resistance to concurrent chemotherapy and radiation therapy (CRT) are incompletely characterized. EXPERIMENTAL DESIGN: We performed integrated whole exome/transcriptome sequencing and immune infiltrate analysis on rectal ade...

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發表在:Clin Cancer Res
Main Authors: Kamran, Sophia C., Lennerz, Jochen K., Margolis, Claire A., Liu, David, Reardon, Brendan, Wankowicz, Stephanie A., Van Seventer, Emily, Tracy, Adam, Wo, Jennifer Y., Carter, Scott L., Willers, Henning, Corcoran, Ryan B., Hong, Theodore S., Van Allen, Eliezer M.
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744983/
https://ncbi.nlm.nih.gov/pubmed/31253631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-0908
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