Integrative molecular characterization of resistance to neoadjuvant chemoradiation in rectal cancer

PURPOSE: Molecular properties associated with complete response or acquired resistance to concurrent chemotherapy and radiation therapy (CRT) are incompletely characterized. EXPERIMENTAL DESIGN: We performed integrated whole exome/transcriptome sequencing and immune infiltrate analysis on rectal ade...

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Publicat a:Clin Cancer Res
Autors principals: Kamran, Sophia C., Lennerz, Jochen K., Margolis, Claire A., Liu, David, Reardon, Brendan, Wankowicz, Stephanie A., Van Seventer, Emily, Tracy, Adam, Wo, Jennifer Y., Carter, Scott L., Willers, Henning, Corcoran, Ryan B., Hong, Theodore S., Van Allen, Eliezer M.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744983/
https://ncbi.nlm.nih.gov/pubmed/31253631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-0908
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