Selective Targeting of Myoblast Fusogenic Signaling and Differentiation-Arrest Antagonizes Rhabdomyosarcoma Cells

Rhabdomyosarcoma (RMS) is an aggressive soft tissue malignancy comprised histologically of skeletal muscle-lineage precursors that fail to exit the cell-cycle and fuse into differentiated syncytial muscle - the underlying pathogenetic mechanisms for which remain unclear. In contrast to myogenic tran...

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Dettagli Bibliografici
Pubblicato in:Cancer Res
Autori principali: Granados, Valerie A., Avirneni-Vadlamudi, Usha, Dalal, Pooja, Scarborough, Samuel R., Galindo, Kathleen A., Mahajan, Priya, Galindo, Rene L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744982/
https://ncbi.nlm.nih.gov/pubmed/31331911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-2096
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