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Pore-modulating toxins exploit inherent slow inactivation to block K(+) channels
Voltage-dependent potassium channels (K(v)s) gate in response to changes in electrical membrane potential by coupling a voltage-sensing module with a K(+)-selective pore. Animal toxins targeting K(v)s are classified as pore blockers, which physically plug the ion conduction pathway, or as gating mod...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6744907/ https://ncbi.nlm.nih.gov/pubmed/31444298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908903116 |
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