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Quantitative Insights into Age-Associated DNA-Repair Inefficiency in Single Cells
Although double-strand break (DSB) repair is essential for a cell’s survival, little is known about how DSB repair mechanisms are affected by age. Here we characterize the impact of cellular aging on the efficiency of single-strand annealing (SSA), a DSB repair mechanism. We measure SSA repair effic...
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| Vydáno v: | Cell Rep |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6744837/ https://ncbi.nlm.nih.gov/pubmed/31433994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.07.082 |
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