Llwytho...

Quantitative Insights into Age-Associated DNA-Repair Inefficiency in Single Cells

Although double-strand break (DSB) repair is essential for a cell’s survival, little is known about how DSB repair mechanisms are affected by age. Here we characterize the impact of cellular aging on the efficiency of single-strand annealing (SSA), a DSB repair mechanism. We measure SSA repair effic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Young, Thomas Z., Liu, Ping, Urbonaite, Guste, Acar, Murat
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744837/
https://ncbi.nlm.nih.gov/pubmed/31433994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.07.082
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!