CD4 T cell sphingosine 1-phosphate receptor (S1PR)1 and S1PR4 and endothelial S1PR2 regulate afferent lymphatic migration

Sphingosine 1-phosphate (S1P) and S1P receptors (S1PR) regulate migration of lymphocytes out of thymus to blood and lymph nodes (LN) to efferent lymph, while their role in other tissue sites is not known. Here we investigated the question of how these molecules regulate leukocyte migration from tiss...

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Pubblicato in:Sci Immunol
Autori principali: Xiong, Yanbao, Piao, Wenji, Brinkman, C. Colin, Li, Lushen, Kulinski, Joseph M., Olivera, Ana, Cartier, Andreane, Hla, Timothy, Hippen, Keli L., Blazar, Bruce R., Schwab, Susan R., Bromberg, Jonathan S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744614/
https://ncbi.nlm.nih.gov/pubmed/30877143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aav1263
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