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Phylogenetic and functional characterisation of the Haemophilus influenzae multidrug efflux pump AcrB

Multidrug resistance in Gram-negative bacteria can arise by the over-expression of multidrug efflux pumps, which can extrude a wide range of antibiotics. Here we describe the ancestral Haemophilus influenzae efflux pump AcrB (AcrB-Hi). We performed a phylogenetic analysis of hundreds of RND-type tra...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Commun Biol
Egile Nagusiak: Zwama, Martijn, Yamaguchi, Akihito, Nishino, Kunihiko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744504/
https://ncbi.nlm.nih.gov/pubmed/31531401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0564-6
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