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ALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy

The nine identified human homologues of E. coli AlkB 2-oxoglutarate (2OG) and Fe(II)-dependent dioxygenase, ALKBH1-8 and FTO, display different substrate specificities and diverse biological functions. Here we discovered the combined overexpression of members of the ALKBH family in head and neck squ...

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Publicat a:Sci Rep
Autors principals: Pilžys, Tomaš, Marcinkowski, Michał, Kukwa, Wojciech, Garbicz, Damian, Dylewska, Małgorzata, Ferenc, Karolina, Mieczkowski, Adam, Kukwa, Andrzej, Migacz, Ewa, Wołosz, Dominika, Mielecki, Damian, Klungland, Arne, Piwowarski, Jan, Poznański, Jarosław, Grzesiuk, Elżbieta
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744417/
https://ncbi.nlm.nih.gov/pubmed/31519943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49550-x
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