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Effect of Posttranslational Modifications on the Structure and Activity of FTO Demethylase
The FTO protein is involved in a wide range of physiological processes, including adipogenesis and osteogenesis. This two-domain protein belongs to the AlkB family of 2-oxoglutarate (2-OG)- and Fe(II)-dependent dioxygenases, displaying N(6)-methyladenosine (N(6)-meA) demethylase activity. The aim of...
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| Yayımlandı: | Int J Mol Sci |
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
MDPI
2021
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8123419/ https://ncbi.nlm.nih.gov/pubmed/33925955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094512 |
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