Intracellular and tissue specific expression of FTO protein in pig: changes with age, energy intake and metabolic status

Genome-wide association studies in the FTO gene have identified SNPs correlating with obesity and type 2 diabetes. In mice, lack of Fto function leads to intrauterine growth retardation and lean phenotype, whereas in human it is lethal. The aim of this study in a pig model was to determine the local...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Ferenc, Karolina, Pilžys, Tomaš, Garbicz, Damian, Marcinkowski, Michał, Skorobogatov, Oleksandr, Dylewska, Małgorzata, Gajewski, Zdzisław, Grzesiuk, Elżbieta, Zabielski, Romuald
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7400765/
https://ncbi.nlm.nih.gov/pubmed/32747736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69856-5
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