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Assessment of methods for predicting the effects of PTEN and TPMT protein variants
Thermodynamic stability is a fundamental property shared by all proteins. Changes in stability due to mutation are a widespread molecular mechanism in genetic diseases. Methods for the prediction of mutation-induced stability change have typically been developed and evaluated on incomplete and/or bi...
Zapisane w:
| Wydane w: | Hum Mutat |
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| Główni autorzy: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6744362/ https://ncbi.nlm.nih.gov/pubmed/31184403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23838 |
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