Assessment of methods for predicting the effects of PTEN and TPMT protein variants

Thermodynamic stability is a fundamental property shared by all proteins. Changes in stability due to mutation are a widespread molecular mechanism in genetic diseases. Methods for the prediction of mutation-induced stability change have typically been developed and evaluated on incomplete and/or bi...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Hum Mutat
Main Authors: Pejaver, Vikas, Babbi, Giulia, Casadio, Rita, Folkman, Lukas, Katsonis, Panagiotis, Kundu, Kunal, Lichtarge, Olivier, Martelli, Pier Luigi, Miller, Maximillian, Moult, John, Pal, Lipika R., Savojardo, Castrense, Yin, Yizhou, Zhou, Yaoqi, Radivojac, Predrag, Bromberg, Yana
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744362/
https://ncbi.nlm.nih.gov/pubmed/31184403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23838
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares