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Predicting the change of exon splicing caused by genetic variant using support vector regression

Alternative splicing can be disrupted by genetic variants that are related to diseases like cancers. Discovering the influence of genetic variations on the alternative splicing will improve the understanding of the pathogenesis of variants. Here, we developed a new approach, PredPSI-SVR to predict t...

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Publicado en:Hum Mutat
Autores principales: Chen, Ken, Lu, Yutong, Zhao, Huiying, Yang, Yuedong
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744342/
https://ncbi.nlm.nih.gov/pubmed/31070294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23785
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