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Evolution of Alternative Splicing Regulation: Changes in Predicted Exonic Splicing Regulators Are Not Associated with Changes in Alternative Splicing Levels in Primates

Alternative splicing is tightly regulated in a spatio-temporal and quantitative manner. This regulation is achieved by a complex interplay between spliceosomal (trans) factors that bind to different sequence (cis) elements. cis-elements reside in both introns and exons and may either enhance or sile...

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Detalhes bibliográficos
Main Authors: Irimia, Manuel, Rukov, Jakob Lewin, Roy, Scott William
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686173/
https://ncbi.nlm.nih.gov/pubmed/19495418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005800
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