Combined genetic disruption of K-Cl cotransporters and Gardos channel KCNN4 rescues erythrocyte dehydration in the SAD mouse model of sickle cell disease.

Ítems similars

• Disruption of erythroid K-Cl cotransporters alters erythrocyte volume and partially rescues erythrocyte dehydration in SAD mice
  per: Rust, Marco B., et al.
  Publicat: (2007)
• Therapy with oral clotrimazole induces inhibition of the Gardos channel and reduction of erythrocyte dehydration in patients with sickle cell disease.
  per: Brugnara, C, et al.
  Publicat: (1996)
• Red blood cell Gardos channel (KCNN4): the essential determinant of erythrocyte dehydration in hereditary xerocytosis
  per: Rapetti-Mauss, Raphaël, et al.
  Publicat: (2017)
• Treatment with oral clotrimazole blocks Ca(2+)-activated K+ transport and reverses erythrocyte dehydration in transgenic SAD mice. A model for therapy of sickle cell disease.
  per: De Franceschi, L, et al.
  Publicat: (1994)
• N-ethylmaleimide activates a Cl(−)-independent component of K(+) flux in mouse erythrocytes
  per: Shmukler, Boris E., et al.
  Publicat: (2013)