Sickle Cell Microvascular Paradox – oxygen supply-demand mismatch

We have previously demonstrated that SCD patients maintain normal global systemic and cerebral oxygen delivery by increasing cardiac output. However, ischemic end-organ injury remains common suggesting that tissue oxygen delivery may be impaired by microvascular dysregulation or damage. To test this...

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Veröffentlicht in:Am J Hematol
Hauptverfasser: Detterich, Jon A., Kato, Roberta, Bush, Adam, Chalacheva, Patjanaporn, Ponce, Derek, De Zoysa, Madushka, Shah, Payal, Khoo, Michael C., Meiselman, Herbert J., Coates, Thomas D., Wood, John C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744275/
https://ncbi.nlm.nih.gov/pubmed/30916797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25476
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