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Patients with sickle cell anemia on simple chronic transfusion protocol show gender differences for hemodynamic and hematologic responses to transfusion

BACKGROUND: Chronic transfusion therapy (CTT) is a mainstay for stroke prophylaxis in sickle cell anemia, but its effects on hemodynamics are poorly characterized. Transfusion improves oxygen carrying capacity, reducing demands for high cardiac output, while decreasing hemoglobin S%, reticulocyte co...

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Главные авторы: Detterich, Jon A., Sangkatumvong, Suvimol, Kato, Roberta, Dongelyan, Ani, Bush, Adam, Khoo, Michael, Meiselman, Herbert J., Coates, Thomas D., Wood, John C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957479/
https://ncbi.nlm.nih.gov/pubmed/23176402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1537-2995.2012.03961.x
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