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Chronic transfusion therapy improves but does not normalize systemic and pulmonary vasculopathy in sickle cell disease
Tricuspid regurgitant (TR) jet velocity and its relationship to pulmonary hypertension has been controversial in sickle cell disease (SCD). Plasma free hemoglobin is elevated in SCD patients and acutely impairs systemic vascular reactivity. We postulated that plasma free hemoglobin would be negative...
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Publicado no: | Blood |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Hematology
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4528063/ https://ncbi.nlm.nih.gov/pubmed/26036801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-12-614370 |
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