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HCF-1 regulates de novo lipogenesis through a nutrient sensitive complex with ChREBP
Carbohydrate response element binding protein (ChREBP) is a key transcriptional regulator of de novo lipogenesis (DNL) in response to carbohydrates and in hepatic steatosis. As such, mechanisms underlying nutrient modulation of ChREBP are under active investigation. Here, we identify Host Cell Facto...
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| Veröffentlicht in: | Mol Cell |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6744259/ https://ncbi.nlm.nih.gov/pubmed/31227231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.05.019 |
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