HCF-1 regulates de novo lipogenesis through a nutrient sensitive complex with ChREBP

Carbohydrate response element binding protein (ChREBP) is a key transcriptional regulator of de novo lipogenesis (DNL) in response to carbohydrates and in hepatic steatosis. As such, mechanisms underlying nutrient modulation of ChREBP are under active investigation. Here, we identify Host Cell Facto...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Cell
Main Authors: Lane, Elizabeth A., Choi, Dong Wook, Garcia-Haro, Luisa, Levine, Zebulon G., Tedoldi, Meghan, Walker, Suzanne, Danial, Nika N.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744259/
https://ncbi.nlm.nih.gov/pubmed/31227231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.05.019
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker