Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion

Caliciviruses are single-stranded RNA viruses with 180 copies of capsid protein comprising the T=3 icosahedral capsids. The main capsid feature is a pronounced protruding (P) domain dimer formed by adjacent subunits on the icosahedral surface while the shell domain forms a tight icosahedral sphere a...

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Bibliographic Details
Published in:J Virol
Main Authors: Sherman, Michael B., Williams, Alexis N., Smith, Hong Q., Nelson, Christopher, Wilen, Craig B., Fremont, Daved H., Virgin, Herbert W., Smith, Thomas J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744230/
https://ncbi.nlm.nih.gov/pubmed/31341042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00970-19
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