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Sphingolipid biosynthesis induces a conformational change in the murine norovirus receptor and facilitates viral infection
Cellular susceptibility to viral infections is in part determined by the presence of a host cellular receptor. Here we use murine norovirus as a model to uncover an unappreciated connection between an intracellular lipid biosynthetic enzyme and a receptor conformation permissive for viral infection....
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| Publicado no: | Nat Microbiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6158067/ https://ncbi.nlm.nih.gov/pubmed/30127493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-018-0221-8 |
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