Llwytho...

Sphingolipid biosynthesis induces a conformational change in the murine norovirus receptor and facilitates viral infection

Cellular susceptibility to viral infections is in part determined by the presence of a host cellular receptor. Here we use murine norovirus as a model to uncover an unappreciated connection between an intracellular lipid biosynthetic enzyme and a receptor conformation permissive for viral infection....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Microbiol
Prif Awduron: Orchard, Robert C., Wilen, Craig B., Virgin, Herbert W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158067/
https://ncbi.nlm.nih.gov/pubmed/30127493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-018-0221-8
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!