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CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus

Murine norovirus (MNoV) is an important model of human norovirus (HNoV) and mucosal virus infection more broadly. Viral receptor utilization is a major determinant of cell tropism, host range, and pathogenesis. The bona fide receptor for HNoV is unknown. Recently, we identified CD300lf as a proteina...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Graziano, Vincent R., Walker, Forrest C., Kennedy, Elizabeth A., Wei, Jin, Ettayebi, Khalil, Strine, Madison S., Filler, Renata B., Hassan, Ebrahim, Hsieh, Leon L., Kim, Arthur S., Kolawole, Abimbola O., Wobus, Christiane E., Lindesmith, Lisa C., Baric, Ralph S., Estes, Mary K., Orchard, Robert C., Baldridge, Megan T., Wilen, Craig B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162533/
https://ncbi.nlm.nih.gov/pubmed/32251490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008242
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