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A Norovirus Uses Bile Salts To Escape Antibody Recognition While Enhancing Receptor Binding

Noroviruses, members of the Caliciviridae family, are the major cause of epidemic gastroenteritis in humans, causing ∼20 million cases annually. These plus-strand RNA viruses have T=3 icosahedral protein capsids with 90 pronounced protruding (P) domain dimers to which antibodies and cellular recepto...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Williams, Alexis N., Sherman, Michael B., Smith, Hong Q., Taube, Stefan, Pettitt, B. Montgomery, Wobus, Christiane E., Smith, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315966/
https://ncbi.nlm.nih.gov/pubmed/33827952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00176-21
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