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MicroRNA-218 promotes osteosarcoma cell apoptosis by downregulating oncogene B lymphoma mouse Moloney leukemia virus insertion region 1

OBJECTIVE: To investigate the tumor-suppressing effect of microRNA-218 (miR-218) in osteosarcoma (OS) and explore its molecular mechanism. METHODS: We examined the expression levels of miR-218 in 68 pairs of OS and adjacent tissue samples using qRT-PCR.Cultured human OS cell line Saos-2 was transfec...

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Publié dans:Nan Fang Yi Ke Da Xue Xue Bao
Format: Artigo
Langue:Inglês
Publié: 南方医科大学学报编辑部 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743892/
https://ncbi.nlm.nih.gov/pubmed/29891444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1673-4254.2018.05.01
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