MicroRNA-218 Inhibits Cell Cycle Progression and Promotes Apoptosis in Colon Cancer by Downregulating BMI1 Polycomb Ring Finger Oncogene

Deregulated miRNAs participate in colorectal carcinogenesis. In this study, miR-218 was found to be downregulated in human colorectal cancer (CRC) by miRNA profile assay. miR-218 was silenced or downregulated in all five colon cancer cells (Caco2, HT29, SW620, HCT116 and LoVo) relative to normal col...

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Autori principali: He, Xinqi, Dong, Yujuan, Wu, Chung Wah, Zhao, Zengren, Ng, Simon S M, Chan, Francis K L, Sung, Joseph J Y, Yu, Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: ScholarOne 2012
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576472/
https://ncbi.nlm.nih.gov/pubmed/23255074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00304
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