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The DEAD-box RNA helicase Ded1 has a role in the translational response to TORC1 inhibition

Ded1 is a DEAD-box RNA helicase with essential roles in translation initiation. It binds to the eukaryotic initiation factor 4F (eIF4F) complex and promotes 48S preinitiation complex assembly and start-site scanning of 5′ untranslated regions of mRNAs. Most prior studies of Ded1 cellular function we...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Aryanpur, Peyman P., Renner, David M., Rodela, Emily, Mittelmeier, Telsa M., Byrd, Aaron, Bolger, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743465/
https://ncbi.nlm.nih.gov/pubmed/31141444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-11-0702
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