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Methylated metabolite of arsenite blocks glycerol production in yeast by inhibition of glycerol-3-phosphate dehydrogenase

The yeast high-osmolarity glycerol (HOG) stress-activated protein kinase Hog1 is activated in response to hyperosmotic stress, inducing the production and retention of glycerol to restore osmotic balance. Hog1 promotes retention of glycerol through closure of the plasma-membrane glycerol channel Fps...

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Библиографические подробности
Опубликовано в: :Mol Biol Cell
Главные авторы: Lee, Jongmin, Levin, David E.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743455/
https://ncbi.nlm.nih.gov/pubmed/31141459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-04-0228
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