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Methylated metabolite of arsenite blocks glycerol production in yeast by inhibition of glycerol-3-phosphate dehydrogenase

The yeast high-osmolarity glycerol (HOG) stress-activated protein kinase Hog1 is activated in response to hyperosmotic stress, inducing the production and retention of glycerol to restore osmotic balance. Hog1 promotes retention of glycerol through closure of the plasma-membrane glycerol channel Fps...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Lee, Jongmin, Levin, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743455/
https://ncbi.nlm.nih.gov/pubmed/31141459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-04-0228
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