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Methylated metabolite of arsenite blocks glycerol production in yeast by inhibition of glycerol-3-phosphate dehydrogenase

The yeast high-osmolarity glycerol (HOG) stress-activated protein kinase Hog1 is activated in response to hyperosmotic stress, inducing the production and retention of glycerol to restore osmotic balance. Hog1 promotes retention of glycerol through closure of the plasma-membrane glycerol channel Fps...

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Pubblicato in:Mol Biol Cell
Autori principali: Lee, Jongmin, Levin, David E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743455/
https://ncbi.nlm.nih.gov/pubmed/31141459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-04-0228
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